Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30506582 | 0.97 | MAPT (0.59) | MAPTSMPD1KMT2ATP53PRSS1 | |
| SCHEMBL25293543 | 0.97 | MAPT (0.59) | MAPTSMPD1KMT2ATP53PRSS1 | |
| SCHEMBL4376688 | 0.94 | MAPT (0.59) | MAPTSMPD1KMT2APRSS1TSHR | |
| SCHEMBL787576 | 0.91 | MAPT (0.59) | MAPTSMPD1KMT2APRSS1TSHR | |
| SCHEMBL1743723 | 0.90 | MAPT (0.57) | MAPTSMPD1KMT2APRSS1TSHR | |
| SCHEMBL13461264 | 0.87 | SMPD1 (0.67) | MAPTSMPD1KMT2ATP53MGLL | |
| SCHEMBL56262 | 0.87 | MAPT (0.60) | MAPTSMPD1KMT2ATP53PRSS1 | |
| SCHEMBL1011139 | 0.87 | MAPT (0.60) | MAPTSMPD1KMT2ATP53PRSS1 | |
| SCHEMBL3372285 | 0.87 | MAPT (0.60) | MAPTSMPD1KMT2ATP53PRSS1 | |
| SCHEMBL2591943 | 0.87 | MAPT (0.60) | MAPTKMT2APRSS1TSHRMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013020461-A1 | PREPARATION METHOD FOR GEFITINIB INTERMEDIATE | 浙江九洲药业股份有限公司 (CN) | 2013-02-14 | — | — | WO | disclosed |