Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18965779 | 0.76 | MEN1 (0.54) | SMN1; SMN2CACNA1GALDH1A1MEN1KMT2A | |
| SCHEMBL14417945 | 0.73 | KMT2A (0.86) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17897619 | 0.73 | POLB (0.54) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5009999 | 0.70 | KMT2A (0.70) | SMN1; SMN2CACNA1GALDH1A1MEN1KMT2A | |
| SCHEMBL31424923 | 0.70 | MEN1 (0.74) | SMN1; SMN2CACNA1GALDH1A1MEN1KMT2A | |
| SCHEMBL31506191 | 0.69 | BAZ2B (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL18998865 | 0.69 | KMT2A (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5012351 | 0.68 | KMT2A (0.75) | SMN1; SMN2CACNA1GALDH1A1MEN1KMT2A | |
| SCHEMBL13012943 | 0.67 | MEN1 (0.47) | ALDH1A1MEN1KMT2APOLBCA2 | |
| SCHEMBL1164954 | 0.67 | KMT2A (0.70) | MEN1KMT2APOLBCA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377523-B2 | Intermediate transfer members | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2013-02-19 | — | — | US | disclosed |