SCHEMBL14707366

SCHEMBL14707366

O=C(OCCO)c1ccc2cc(C(=O)OCCOC(=O)c3ccc4cc(C(=O)OCCOC(=O)c5ccc6ccc(C(=O)OCCO)cc6c5)ccc4c3)ccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.50
DRD3 P35462 1/20 0.48
SLC7A5 Q01650 1/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
SERPINE1 P05121 3/20 0.43
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
POLB P06746 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
ALDH1A1 P00352 1/20 0.40
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465188 0.94 HRH3 (0.50) HRH3DRD3SLC7A5KDM4ESERPINE1
SCHEMBL16606218 0.91 HRH3 (0.59) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL28263296 0.90 SLC7A5 (0.46) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL13698260 0.88 SLC7A5 (0.45) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL17929895 0.88 SERPINE1 (0.50) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL7156008 0.88 KDM4E (0.50) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL30741570 0.88 KDM4E (0.50) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL17929896 0.88 SERPINE1 (0.50) HRH3DRD3SLC7A5KDM4EMAPT
SCHEMBL9814333 0.86 PTPN11 (0.53) HRH3DRD3KDM4EMAPTHTT
SCHEMBL19360474 0.85 HRH3 (0.54) HRH3DRD3KDM4EMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852697-B2 Cellulose acetate film, and polarizing plate and liquid crystal display device which are made using same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2014-10-07 US disclosed
US-8852697-B2 Cellulose acetate film, and polarizing plate and liquid crystal display device which are made using same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2014-10-07 US disclosed
US-20130045340-A1 CELLULOSE ACETATE FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE WHICH ARE MADE USING SAME KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-02-21 US disclosed
US-20130045340-A1 CELLULOSE ACETATE FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE WHICH ARE MADE USING SAME KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-02-21 US disclosed