Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119673 | 0.85 | CYP1A1 (0.70) | CYP1A1HTTSMN1; SMN2GHSRHIF1A | |
| SCHEMBL16178221 | 0.83 | CYP1A1 (0.71) | CYP1A1HTTSMN1; SMN2GHSRL3MBTL1 | |
| SCHEMBL16178226 | 0.83 | CYP1A1 (0.72) | CYP1A1HTTSMN1; SMN2GHSRHIF1A | |
| SCHEMBL14217387 | 0.82 | CYP1A1 (0.63) | CYP1A1HTTSMN1; SMN2GHSRHIF1A | |
| SCHEMBL16186796 | 0.80 | CYP1A1 (0.64) | CYP1A1HTTSMN1; SMN2GHSRHIF1A | |
| SCHEMBL16186811 | 0.80 | CYP1A1 (0.65) | CYP1A1HTTSMN1; SMN2GHSRHIF1A | |
| SCHEMBL14119726 | 0.75 | CYP1A1 (0.63) | CYP1A1HTTSMN1; SMN2HIF1ANPSR1 | |
| SCHEMBL2303592 | 0.73 | HTT (0.52) | CYP1A1HTTSMN1; SMN2GHSRHIF1A | |
| SCHEMBL13150525 | 0.73 | CYP1A1 (0.47) | CYP1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL14217285 | 0.72 | HTT (0.50) | HTTSMN1; SMN2GHSRHIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023274-A1 | SUBSTITUTED 2-IMIDAZOLIDINONES AND 2-IMIDAZOLONES AND THEIR USE IN THE TREATMENT OF CANCER | UNIVERSITE LAVAL (CA) | 2013-02-21 | — | — | WO | disclosed |