Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 11/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302728 | 0.94 | CYP1A1 (0.58) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2300655 | 0.86 | CYP1A1 (0.50) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2302983 | 0.85 | GAA (0.61) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2234141 | 0.85 | GAA (0.61) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2303527 | 0.83 | GAA (0.45) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2302548 | 0.82 | CYP1A1 (0.64) | CYP1A1GAASCN9A | |
| SCHEMBL2304336 | 0.82 | CYP1A1 (0.45) | CYP1A1GAALMNASMN1; SMN2SCN9A | |
| SCHEMBL2304867 | 0.81 | CYP1A1 (0.44) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2235366 | 0.81 | CYP1A1 (0.47) | CYP1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL2299605 | 0.80 | CYP1A1 (0.43) | CYP1A1GAALMNASMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023274-A1 | SUBSTITUTED 2-IMIDAZOLIDINONES AND 2-IMIDAZOLONES AND THEIR USE IN THE TREATMENT OF CANCER | UNIVERSITE LAVAL (CA) | 2013-02-21 | — | — | WO | disclosed |