Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 19/20 | 0.47 |
| ▸ | GUCY1A2 | P33402 | 19/20 | 0.47 |
| ▸ | GUCY1A1 | Q02108 | 19/20 | 0.47 |
| ▸ | GUCY1B1 | Q02153 | 19/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233357 | 0.91 | MEN1 (0.47) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL14709870 | 0.91 | GUCY1B2 (0.48) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL14697250 | 0.90 | GUCY1B2 (0.47) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL14709801 | 0.89 | GUCY1B2 (0.47) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL15153415 | 0.87 | GUCY1B2 (0.49) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL3236272 | 0.87 | GUCY1B2 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1NPC1 | |
| SCHEMBL3234865 | 0.87 | GUCY1B2 (0.44) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL14709809 | 0.87 | GUCY1B2 (0.50) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL3230062 | 0.87 | GUCY1B2 (0.44) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1NPC1 | |
| SCHEMBL14709674 | 0.86 | GUCY1B2 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025425-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-21 | — | — | WO | disclosed |