Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14790390 | 0.89 | LPAR1 (0.45) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14710262 | 0.87 | LPAR1 (0.55) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14710241 | 0.81 | LPAR1 (0.51) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14710711 | 0.79 | SMN1; SMN2 (0.41) | CYP2C9 | |
| SCHEMBL14710239 | 0.79 | LPAR1 (0.61) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14790389 | 0.76 | LPAR1 (0.43) | LPAR1LPAR3 | |
| SCHEMBL14711092 | 0.76 | LPAR1 (0.44) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14790385 | 0.73 | LPAR1 (0.47) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14712095 | 0.73 | LPAR1 (0.57) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14710638 | 0.72 | LPAR1 (0.47) | LPAR1LPAR3ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |