Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 10/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.37 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14790388 | 0.83 | LPAR1 (0.51) | LPAR1LPAR3 | |
| SCHEMBL14712115 | 0.78 | LPAR1 (0.48) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL14710709 | 0.74 | POLB (0.51) | CYP2C9 | |
| SCHEMBL14711438 | 0.73 | LPAR1 (0.45) | LPAR1LPAR3HCAR2GRM5OPRM1 | |
| SCHEMBL14710336 | 0.73 | LPAR1 (0.48) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL28571893 | 0.73 | KLK7 (0.54) | LPAR1LPAR3HCAR2GRM5OPRM1 | |
| SCHEMBL28568899 | 0.73 | KLK7 (0.54) | LPAR1LPAR3HCAR2GRM5OPRM1 | |
| SCHEMBL14790385 | 0.73 | LPAR1 (0.47) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL9915924 | 0.72 | LPAR1 (0.48) | LPAR1LPAR3HCAR2OPRM1 | |
| SCHEMBL9915926 | 0.72 | LPAR1 (0.52) | LPAR1LPAR3ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |