Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14790552 | 0.87 | MAPT (0.54) | TSHRMAPTTHRBTP53MEN1 | |
| SCHEMBL14710823 | 0.87 | TSHR (0.48) | TSHRMAPTTHRBPSMB8TP53 | |
| SCHEMBL14710784 | 0.83 | TSHR (0.44) | TSHRMAPTTHRBTP53MEN1 | |
| SCHEMBL14790554 | 0.79 | LPAR1 (0.48) | TSHRMAPTTHRBPSMB8TP53 | |
| SCHEMBL14710753 | 0.78 | LPAR1 (0.47) | TSHRMAPTTHRBPSMB8TP53 | |
| SCHEMBL13763195 | 0.72 | PSMB8 (0.54) | PSMB8SMN1; SMN2 | |
| Water SCHEMBL27835379 | 0.70 | PSMB8 (0.52) | PSMB8SMN1; SMN2 | |
| SCHEMBL5353096 | 0.70 | CA1 (0.35) | TSHRPSMB8KMT2ASMN1; SMN2 | |
| SCHEMBL31171492 | 0.70 | SMN1; SMN2 (0.36) | TSHRPSMB8SMN1; SMN2 | |
| SCHEMBL29159120 | 0.70 | STAT5B (0.37) | MAPTPSMB8MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |