Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 5/20 | 0.59 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25044743 | 0.89 | SLC5A1 (0.57) | SLC5A1SLC5A2CA1CA2CA4 | |
| SCHEMBL15897976 | 0.87 | CA12 (0.53) | SLC5A1SLC5A2CA1CA2CA9 | |
| SCHEMBL16697029 | 0.86 | SLC5A1 (0.57) | SLC5A1SLC5A2CA1CA2CA4 | |
| SCHEMBL30282905 | 0.86 | TP53 (0.49) | SLC5A1SLC5A2TP53ALOX12SMN1; SMN2 | |
| SCHEMBL25045387 | 0.86 | KMT2A (0.56) | SLC5A1SLC5A2CA1CA2CA4 | |
| SCHEMBL20028111 | 0.86 | TP53 (0.66) | SLC5A1SLC5A2TP53ALOX12SMN1; SMN2 | |
| SCHEMBL16697431 | 0.86 | SLC5A1 (0.46) | SLC5A1SLC5A2CA1CA2CA4 | |
| SCHEMBL14711070 | 0.85 | SLC5A1 (0.56) | SLC5A1SLC5A2CA1CA2CA4 | |
| SCHEMBL15882063 | 0.85 | SMN1; SMN2 (0.65) | SLC5A1SLC5A2TP53ALOX12SMN1; SMN2 | |
| SCHEMBL25044788 | 0.83 | ADORA1 (0.47) | SLC5A1SLC5A2TP53ALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343695-A1 | Lysophosphatidic Acid Receptor 1 Antagonists as Migrastatics for Cancer | LAKEHEAD UNIVERSITY (CA) | 2024-10-17 | — | — | US | disclosed |
| US-20240317709-A1 | Lysophosphatidic Acid Receptor Antagonists for Breast Cancer Treatment | UNIV LAKEHEAD (CA) | 2024-09-26 | — | — | US | disclosed |
| US-8975235-B2 | Lysophosphatidic acid receptor antagonists | INTERMUNE, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-8975235-B2 | Lysophosphatidic acid receptor antagonists | INTERMUNE, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20130072449-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072449-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317709-A1 | Lysophosphatidic Acid Receptor Antagonists for Breast Cancer Treatment | LPAR3, LPAR1, LPAR4 | SLC5A1 1889/4885SLC5A2 3403/4885CA1 2809/4885 |
| US-20130072449-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | SLC5A1 1747/4885SLC5A2 1833/4885CA1 1975/4885 |
| US-20240343695-A1 | Lysophosphatidic Acid Receptor 1 Antagonists as Migrastatics for Cancer | LPAR1, LPAR3, LPAR4 | SLC5A1 2018/4885SLC5A2 3642/4885CA1 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.