SCHEMBL1471286

SCHEMBL1471286

Fc1cc[c]c(Br)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6228844 0.79
SCHEMBL9367007 0.75
SCHEMBL10677998 0.75
SCHEMBL6992340 0.75
SCHEMBL78405 0.72
SCHEMBL6988996 0.70 CA12 (0.32)
SCHEMBL17514716 0.70
SCHEMBL20943628 0.70
SCHEMBL17514460 0.70
SCHEMBL16797100 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111212647-B Dihydro oxadiazinones 拜耳股份有限公司 2024-05-14 CN disclosed
US-20240043385-A1 ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE INTERVET INC. (US) 2024-02-08 US disclosed
US-20240043446-A1 ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE INTERVET INC. (US) 2024-02-08 US disclosed
EP-4259606-A1 ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE Intervet International B.V. (NL) 2023-10-18 EP disclosed
EP-4259636-A1 ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE Intervet International B.V. (NL) 2023-10-18 EP disclosed
US-20230148316-A1 ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE INTERVET INC. (US) 2023-05-11 US disclosed
US-20230110397-A1 ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE INTERVET INC. (US) 2023-04-13 US disclosed
EP-4101852-A1 PYRIDOPYRIMIDINONE COMPOUND AND APPLICATION THEREOF Bebetter Med Inc. (CN) 2022-12-14 EP disclosed
EP-4077322-A1 ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE Intervet International B.V. (NL) 2022-10-26 EP disclosed
EP-4077281-A1 ANTHELMINTIC COMPOUNDS COMPRISING A QUINOLINE STRUCTURE Intervet International B.V. (NL) 2022-10-26 EP disclosed
US-20090215820-A1 NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS ANIONA APS (DK) 2009-08-27 US disclosed
US-7547788-B2 Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors NEUROSEARCH A/S (DK) 2009-06-16 US disclosed
WO-2008108378-A2 BICYCLIC OXOMORPHOLINE DERIVATIVE EISAI R & D MANAGEMENT CO., LTD. (JP) 2008-09-12 WO disclosed
US-20070167487-A1 Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors ANIONA APS (DK) 2007-07-19 US disclosed
EP-1761493-A2 ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS NEUROSEARCH A/S (DK) 2007-03-14 EP disclosed
WO-2005123679-A2 ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS NEUROSEARCH A/S (DK) 2005-12-29 WO disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed