Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639602 | 0.84 | CCR1 (0.66) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3638408 | 0.77 | CCR1 (0.40) | CCR1 | |
| SCHEMBL3057651 | 0.71 | CCR1 (0.64) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3468992 | 0.71 | CCR1 (0.72) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1637558 | 0.71 | CCR1 (0.66) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1638427 | 0.70 | CCR1 (0.70) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3780578 | 0.69 | CCR1 (0.61) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3080228 | 0.69 | CCR1 (0.63) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3063748 | 0.69 | CCR1 (0.63) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3772008 | 0.68 | CCR1 (0.59) | CCR1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383630-B2 | Azaindazole compounds and methods of use | CHEMOCENTRYX, INC. (US) | 2013-02-26 | — | — | US | claimed |