Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 10/20 | 0.39 |
| ▸ | CASP7 | P55210 | 10/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9895127 | 0.81 | CYP1A2 (0.47) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL9895612 | 0.78 | HSD17B10 (0.45) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL14715247 | 0.74 | CYP1A2 (0.46) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL9903971 | 0.72 | CYP1A2 (0.40) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL15279147 | 0.72 | POLB (0.46) | CYP1A2HSD17B10POLBALDH1A1CYP2C9 | |
| SCHEMBL454637 | 0.70 | CYP1A2 (0.40) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL17427443 | 0.69 | POLB (0.41) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13733869 | 0.67 | CYP1A2 (0.48) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL13736743 | 0.66 | CYP1A2 (0.49) | CYP1A2HSD17B10CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL17427408 | 0.64 | POLB (0.41) | POLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562174-A1 | Herbicidal 6-Oxo-1,6-dihydropyrimidin-5-carboxamides and 2-Oxo-1,2-dihydropyridin-3-carboxamides | Bayer Cropscience AG (DE) | 2013-02-27 | — | — | EP | disclosed |