Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568170 | 0.85 | MAP4K4 (0.66) | MAP4K4 | |
| SCHEMBL5491465 | 0.82 | MAP4K4 (0.73) | MAP4K4 | |
| SCHEMBL5500217 | 0.82 | MAP4K4 (0.64) | MAP4K4 | |
| SCHEMBL5494600 | 0.80 | MAP4K4 (0.67) | MAP4K4 | |
| SCHEMBL5495130 | 0.78 | MAP4K4 (0.66) | MAP4K4 | |
| SCHEMBL15587448 | 0.78 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15537334 | 0.77 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL5491473 | 0.76 | MAP4K4 (0.63) | MAP4K4 | |
| SCHEMBL5498709 | 0.76 | MAP4K4 (0.68) | MAP4K4 | |
| SCHEMBL15587652 | 0.74 | MAP4K4 (1.00) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836174-B1 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2013-02-27 | — | — | EP | claimed |