Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527030 | 1.00 | ITGB1 (0.53) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL8526966 | 1.00 | ITGB1 (0.53) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL27850294 | 0.98 | ITGB1 (0.52) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL22163853 | 0.98 | ITGB1 (0.52) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL22163849 | 0.98 | ITGB1 (0.52) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL29242244 | 0.98 | ITGB1 (0.52) | ITGB1ITGA4CA2CA1CA12 | |
| Magnesium SCHEMBL29614114 | 0.98 | ITGB1 (0.52) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL28830891 | 0.98 | ITGB1 (0.52) | ITGB1ITGA4CA2CA1CA12 | |
| Acetaldehyde SCHEMBL28427100 | 0.94 | ITGB1 (0.49) | ITGB1ITGA4CA2CA1CA12 | |
| SCHEMBL29242177 | 0.88 | ITGB1 (0.47) | ITGB1ITGA4CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736939-B | Method for promoting enzymatic preparation of (2R, 3S) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114736939-A | Method for promoting enzymatic preparation of (2R, 3S) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-07-12 | — | — | CN | claimed |
| EP-1948594-B1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2013-02-27 | — | — | EP | claimed |
| CN-118853641-A | L-threonine aldolase and preparation method and application thereof | 弈柯莱生物科技(重庆)有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117646044-A | Method for synthesizing (1R, 2R) -4-methylsulfonyl benzene silk amino alcohol by multi-enzyme cascade and application thereof | 福州大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-117646044-A | Method for synthesizing (1R, 2R) -4-methylsulfonyl benzene silk amino alcohol by multi-enzyme cascade and application thereof | 福州大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-117384877-A | Serine hydroxymethyl transferase and application thereof in preparation of (2S, 3R) -p-methylsulfonyl phenylserine | 弈柯莱生物科技(集团)股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115433727-B | L-threonine aldolase and preparation method and application thereof | 弈柯莱生物科技(集团)股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116410967-A | L-threonine aldolase and preparation method and application thereof | 弈柯莱生物科技(重庆)有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-115433727-A | L-threonine aldolase, and preparation method and application thereof | 弈柯莱生物科技(上海)股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114958935-B | Synthesis method of chiral (2S, 3R) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-114736939-B | Method for promoting enzymatic preparation of (2R, 3S) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114958935-A | Synthesis method of chiral (2S,3R) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114736939-A | Method for promoting enzymatic preparation of (2R, 3S) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736939-A | Method for promoting enzymatic preparation of (2R, 3S) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736939-A | Method for promoting enzymatic preparation of (2R, 3S) -p-methylsulfonylphenylserine | 山东国邦药业有限公司 | 2022-07-12 | — | — | CN | disclosed |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-17 | — | — | US | disclosed |
| US-11046653-B2 | — | — | 2021-06-29 | — | — | US | disclosed |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046653-B2 | — | CYP4F11, NOTUM, CYP2F1 | ITGB1 2474/4885ITGA4 2303/4885CA2 1479/4885 |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, NOTUM, WEE2 | ITGB1 3279/4885ITGA4 3121/4885CA2 2685/4885 |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | WEE1, NOTUM, WEE2 | ITGB1 3279/4885ITGA4 3121/4885CA2 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.