Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415413 | 0.87 | KMT2A (0.45) | PPARGPPARAFABP5FABP7TLR2 | |
| SCHEMBL17339044 | 0.87 | KMT2A (0.45) | PPARGPPARAFABP5FABP7TLR2 | |
| SCHEMBL29203790 | 0.87 | KMT2A (0.45) | PPARGPPARAFABP5FABP7TLR2 | |
| SCHEMBL29203732 | 0.87 | KMT2A (0.45) | PPARGPPARAFABP5FABP7TLR2 | |
| SCHEMBL570371 | 0.84 | KMT2A (0.49) | PPARGPPARAFABP5FABP7TLR2 | |
| SCHEMBL27805682 | 0.83 | PPARG (0.40) | PPARGPPARAFABP5FABP7TLR2 | |
| SCHEMBL2040433 | 0.78 | KMT2A (0.50) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL1829604 | 0.76 | FABP5 (0.50) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL1829602 | 0.76 | FABP5 (0.50) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL21838009 | 0.75 | TLR2 (0.58) | TLR2CASP3MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952095-B2 | Cross-linking agents for hydrogels that contain cleavable peptides and short-chain polymers | CELLENDES GMBH (DE) | 2015-02-10 | — | — | US | disclosed |
| US-20130052736-A1 | CROSS-LINKING AGENTS FOR HYDROGELS THAT CONTAIN CLEAVABLE PEPTIDES AND SHORT-CHAIN POLYMERS | CELLENDES GMBH (DE) | 2013-02-28 | — | — | US | disclosed |