Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14717676 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14718203 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14717470 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14717475 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14718161 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14718057 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14718027 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14717466 | 0.99 | LPAR3 (0.33) | TSHRLPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14717577 | 0.95 | TSHR (0.35) | TSHRCYP3A4 | |
| SCHEMBL14717398 | 0.90 | CYP3A4 (0.37) | TSHRLPAR3LPAR1LPAR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053287-A1 | SYNTHETIC LUBRICANT | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-02-28 | — | — | US | disclosed |