SCHEMBL14719960

SCHEMBL14719960

[N-]=[N+]=Nc1cc(C(=O)O)cc(C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 19/20 0.59
ALB P02768 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145518 1.00 FOLH1 (0.59) FOLH1ALB
SCHEMBL14728970 0.97 FOLH1 (0.62) FOLH1ALB
SCHEMBL20492756 0.97 FOLH1 (0.62) FOLH1ALB
SCHEMBL18145830 0.97 FOLH1 (0.62) FOLH1ALB
SCHEMBL14719961 0.93 FOLH1 (0.53) FOLH1ALB
SCHEMBL14721592 0.91 FOLH1 (0.59) FOLH1
SCHEMBL14719978 0.88 FOLH1 (0.57) FOLH1ALB
SCHEMBL18145453 0.88 FOLH1 (0.57) FOLH1ALB
SCHEMBL22712886 0.88 FOLH1 (0.73) FOLH1ALB
SCHEMBL14729376 0.88 FOLH1 (0.73) FOLH1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 FOLH1 4/4885ALB 1116/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 FOLH1 4/4885ALB 1041/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885ALB 1023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.