SCHEMBL14720439

SCHEMBL14720439

C=C(CC(=O)OCCCCCCC(C)C)C(=O)OCCCCCCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
FAAH O00519 2/20 0.38
NAAA Q02083 1/20 0.37
RARB P10826 1/20 0.36
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
CYP19A1 P11511 1/20 0.35
KDM4C Q9H3R0 2/20 0.33
KDM4A O75164 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
ACHE P22303 1/20 0.33
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9955895 1.00 TSHR (0.41) TSHRFAAHNAAARARBRAD52
SCHEMBL12501996 1.00 TSHR (0.41) TSHRFAAHNAAARARBRAD52
SCHEMBL12501899 0.98 TSHR (0.39) TSHRFAAHNAAARARBRAD52
SCHEMBL12502152 0.93 CYP19A1 (0.36) TSHRFAAHNAAARARBRAD52
SCHEMBL27399080 0.87 TSHR (0.41) TSHRRARBTDP1POLBAPEX1
SCHEMBL28327465 0.87 TSHR (0.41) TSHRRARBTDP1POLBAPEX1
SCHEMBL30115065 0.87 TSHR (0.41) TSHRRARBTDP1POLBAPEX1
SCHEMBL29288254 0.87 TSHR (0.41) TSHRRARBTDP1POLBAPEX1
SCHEMBL24993405 0.87 RARB (0.39) TSHRFAAHNAAARARBRAD52
SCHEMBL24992254 0.87 RARB (0.39) TSHRFAAHNAAARARBRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013028307-A1 DERIVATIVES OF HYDROCARBON TERPENES Amyris, Inc. (US) 2013-02-28 WO disclosed