Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721030 | 0.85 | CCR1 (0.37) | CCR1OPRM1OPRD1OPRL1HTR1D | |
| SCHEMBL14720746 | 0.82 | HRH3 (0.38) | CCR1OPRL1 | |
| SCHEMBL14720847 | 0.80 | HRH3 (0.38) | CCR1OPRM1OPRL1 | |
| SCHEMBL14720603 | 0.79 | HRH3 (0.36) | CCR1OPRL1 | |
| SCHEMBL14720966 | 0.79 | HRH3 (0.36) | CCR1OPRL1 | |
| SCHEMBL14720807 | 0.79 | HRH3 (0.36) | CCR1OPRL1 | |
| SCHEMBL14720602 | 0.79 | HRH3 (0.36) | CCR1OPRL1 | |
| SCHEMBL14720811 | 0.77 | HRH3 (0.36) | CCR1OPRM1OPRL1 | |
| SCHEMBL14720813 | 0.77 | HRH3 (0.36) | CCR1OPRM1OPRL1 | |
| SCHEMBL14721107 | 0.77 | HRH3 (0.36) | CCR1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |