Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720675 | 0.80 | HRH3 (0.36) | HRH3OPRL1 | |
| SCHEMBL14720746 | 0.80 | HRH3 (0.38) | HRH3OPRL1 | |
| SCHEMBL14720847 | 0.78 | HRH3 (0.38) | HRH3OPRL1 | |
| SCHEMBL14720465 | 0.77 | HRH3 (0.36) | HRH3OPRL1 | |
| SCHEMBL14720602 | 0.77 | HRH3 (0.36) | HRH3OPRL1 | |
| SCHEMBL14720807 | 0.77 | HRH3 (0.36) | HRH3OPRL1 | |
| SCHEMBL14720966 | 0.77 | HRH3 (0.36) | HRH3OPRL1 | |
| SCHEMBL14720603 | 0.77 | HRH3 (0.36) | HRH3OPRL1 | |
| SCHEMBL14720541 | 0.77 | POLB (0.43) | SLC6A4 | |
| SCHEMBL14720770 | 0.76 | HRH3 (0.34) | TACR1HRH3OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |