Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441753 | 0.93 | TSHR (0.48) | TSHRMAPK8 | |
| SCHEMBL2368898 | 0.89 | — | — | |
| SCHEMBL2369051 | 0.89 | — | — | |
| SCHEMBL473550 | 0.89 | — | — | |
| Hydrogen Peroxide SCHEMBL28037399 | 0.87 | TSHR (0.35) | TSHRDPP4SHBG | |
| SCHEMBL10876165 | 0.82 | TSHR (0.32) | TSHRSHBG | |
| SCHEMBL6132259 | 0.82 | TSHR (0.32) | TSHRSHBG | |
| SCHEMBL25056729 | 0.82 | — | — | |
| SCHEMBL245842 | 0.81 | — | — | |
| SCHEMBL14270059 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |