Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 8/20 | 0.43 |
| ▸ | RET | P07949 | 5/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730278 | 1.00 | NTRK1 (0.43) | NTRK1RETSMOMCHR1DPP4 | |
| SCHEMBL14730294 | 0.92 | NTRK1 (0.42) | NTRK1RETSMOMCHR1DPP4 | |
| SCHEMBL14723500 | 0.92 | NTRK1 (0.42) | NTRK1RETSMOMCHR1DPP4 | |
| SCHEMBL14723078 | 0.90 | RET (0.37) | RETSMODPP4 | |
| SCHEMBL14730210 | 0.90 | RET (0.37) | RETSMODPP4 | |
| SCHEMBL10058396 | 0.89 | NTRK1 (0.40) | NTRK1RETMCHR1DPP4F2R | |
| SCHEMBL1720753 | 0.89 | NTRK1 (0.40) | NTRK1RETMCHR1F2R | |
| SCHEMBL609468 | 0.89 | NTRK1 (0.40) | NTRK1RETMCHR1F2R | |
| SCHEMBL14723597 | 0.88 | NTRK1 (0.43) | NTRK1RETMCHR1 | |
| SCHEMBL14730180 | 0.88 | NTRK1 (0.43) | NTRK1RETMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |