Oxirane

Oxirane

SCHEMBL14722328

C1CO1.CC(C)C(=O)Br

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138447 0.83
Bromide SCHEMBL28988959 0.79
Bromide SCHEMBL29623017 0.79
Oxirane SCHEMBL15286473 0.78
Dioxane SCHEMBL20593971 0.75 SMN1; SMN2 (0.41)
Dioxane SCHEMBL28559564 0.75 SMN1; SMN2 (0.46)
Dioxane SCHEMBL3231271 0.73 SMN1; SMN2 (0.40)
Lactic Acid SCHEMBL6566944 0.69
Lactic Acid SCHEMBL17492264 0.69 TP53 (0.69)
Acetone SCHEMBL8812242 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2747753-A1 ATOM TRANSFER RADICAL POLYMERIZATION UNDER BIOLOGICALLY COMPATIBLE CONDITIONS Carnegie Mellon University (US) 2014-07-02 EP disclosed
WO-2013028756-A1 ATOM TRANSFER RADICAL POLYMERIZATION UNDER BIOLOGICALLY COMPATIBLE CONDITIONS CARNEGIE MELLON UNIVERSITY (US) 2013-02-28 WO disclosed