Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162871 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL457993 | 0.83 | NPC1 (0.84) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL13162942 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL13161963 | 0.81 | NPC1 (0.65) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL13164090 | 0.80 | NPC1 (0.69) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL13162641 | 0.80 | NPC1 (0.90) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL13162659 | 0.80 | NPC1 (0.97) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL2394499 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL23573548 | 0.79 | NPC1 (0.77) | SMN1; SMN2GLANPC1RAB9APOLB | |
| SCHEMBL23573547 | 0.79 | NPC1 (0.77) | SMN1; SMN2GLANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |