Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.73 |
| ▸ | CCR8 | P51685 | 1/20 | 0.73 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 5/20 | 0.39 |
| ▸ | IDH2 | P48735 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911967 | 0.85 | — | — | |
| SCHEMBL111063 | 0.85 | — | — | |
| SCHEMBL30511194 | 0.85 | CCR1 (1.00) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL1071454 | 0.85 | CYP3A4 (0.50) | CCR1CCR8CYP3A4TSHRIDH1 | |
| SCHEMBL196966 | 0.85 | CCR1 (1.00) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL30492599 | 0.85 | CYP3A4 (0.50) | CCR1CCR8CYP3A4TSHRIDH1 | |
| SCHEMBL29388304 | 0.85 | CCR1 (1.00) | CCR1CCR8METAP2CYP2A6NOS3 | |
| Hydrochloric Acid SCHEMBL4622483 | 0.83 | — | — | |
| SCHEMBL29751933 | 0.83 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 | |
| SCHEMBL20557390 | 0.83 | CCR1 (0.94) | CCR1CCR8METAP2CYP2A6NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |