Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18381106 | 0.88 | KMT2A (0.62) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL13557797 | 0.88 | KMT2A (0.62) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL13425195 | 0.88 | HDAC1 (0.68) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL16436962 | 0.88 | KMT2A (0.50) | KMT2AALDH1A1LMNAHSD17B10HTT | |
| SCHEMBL13557799 | 0.87 | KMT2A (0.64) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL13425158 | 0.86 | PRSS1 (0.56) | KMT2AALDH1A1LMNAHSD17B10HTT | |
| SCHEMBL13557791 | 0.85 | KMT2A (0.75) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL14723639 | 0.85 | KMT2A (0.54) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL16436960 | 0.83 | TOP2A (0.51) | L3MBTL1ALDH1A1MAPTCNR1 | |
| SCHEMBL14984017 | 0.83 | KMT2A (0.64) | L3MBTL1KMT2AALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383855-B2 | Histone deacetylase inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-02-26 | — | — | US | disclosed |