Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 18/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706923 | 0.93 | SCD (0.66) | SCDOPRD1KCNH2 | |
| SCHEMBL6737464 | 0.92 | SCD (0.63) | SCD | |
| SCHEMBL3697646 | 0.92 | SCD (0.66) | SCDOPRD1KCNH2 | |
| SCHEMBL3697648 | 0.92 | SCD (0.66) | SCDOPRD1KCNH2 | |
| SCHEMBL6783363 | 0.92 | SCD (0.66) | SCDOPRD1KCNH2 | |
| SCHEMBL6737763 | 0.91 | SCD (0.60) | SCDOPRD1KCNH2 | |
| SCHEMBL14723894 | 0.90 | SCD (0.63) | SCD | |
| SCHEMBL6737497 | 0.87 | SCD (0.67) | SCD | |
| SCHEMBL6737345 | 0.87 | SCD (0.66) | SCD | |
| SCHEMBL3708364 | 0.87 | SCD (0.66) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383643-B2 | Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase | MERCK CANADA INC. (CA) | 2013-02-26 | — | — | US | disclosed |