Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637676 | 0.89 | CCR1 (0.73) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1638663 | 0.86 | CCR1 (0.76) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1639474 | 0.86 | CCR1 (0.75) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1639844 | 0.85 | CCR1 (0.72) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1638717 | 0.85 | CCR1 (0.74) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3464057 | 0.85 | CCR1 (0.71) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1637482 | 0.84 | CCR1 (0.73) | CCR1CYP2C19KCNH2 | |
| SCHEMBL12766295 | 0.84 | CCR1 (0.73) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1639649 | 0.84 | CCR1 (0.73) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1639727 | 0.84 | CCR1 (0.73) | CCR1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383630-B2 | Azaindazole compounds and methods of use | CHEMOCENTRYX, INC. (US) | 2013-02-26 | — | — | US | disclosed |