Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12602474 | 0.92 | CNR1 (0.35) | CNR1DRD2HTR7KCNH2HRH3 | |
| SCHEMBL1128273 | 0.90 | CNR1 (0.43) | CNR1DRD2HTR7KCNH2HRH3 | |
| SCHEMBL1985069 | 0.87 | CNR1 (0.42) | CNR1KCNH2HRH3CNR2 | |
| SCHEMBL1987339 | 0.85 | CNR1 (0.41) | CNR1DRD2HTR7KCNH2HTR1A | |
| SCHEMBL1128022 | 0.83 | CNR1 (0.40) | CNR1HTR1ACNR2ALDH1A1 | |
| SCHEMBL1127694 | 0.82 | CNR1 (0.40) | CNR1DRD2HTR7KCNH2HRH3 | |
| SCHEMBL1987361 | 0.81 | CNR1 (0.40) | CNR1HTR1ACNR2 | |
| SCHEMBL1988692 | 0.80 | CNR1 (0.46) | CNR1HTR1ACNR2 | |
| SCHEMBL1990962 | 0.80 | CNR1 (0.42) | CNR1HTR1ACNR2ALDH1A1 | |
| SCHEMBL1985030 | 0.77 | CNR1 (0.41) | CNR1KCNH2HTR1ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383666-B2 | Pyrrole derivatives, preparation of same and therapeutic application thereof | SANOFI (FR) | 2013-02-26 | — | — | US | disclosed |