SCHEMBL14723989

SCHEMBL14723989

CSC[C@H](O)[C@@H](CO)CN(C)Cc1c[nH]c2c(N)ncnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTAP Q13126 19/20 1.00
PNP P00491 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12894124 1.00 MTAP (1.00) MTAPPNP
SCHEMBL1223506 1.00 MTAP (1.00) MTAPPNP
SCHEMBL1222923 0.93 MTAP (1.00) MTAPPNP
SCHEMBL1222947 0.93 MTAP (1.00) MTAPPNP
SCHEMBL1223155 0.93 MTAP (1.00) MTAPPNP
SCHEMBL1223012 0.93 MTAP (1.00) MTAPPNP
SCHEMBL1221607 0.89 MTAP (1.00) MTAP
SCHEMBL1222149 0.89 MTAP (1.00) MTAP
SCHEMBL1223230 0.89 MTAP (1.00) MTAP
SCHEMBL1223121 0.89 MTAP (1.00) MTAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383636-B2 Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase INDUSTRIAL RESEARCH LIMITED (NZ) 2013-02-26 US disclosed