Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14683514 | 0.93 | GLP1R (0.46) | GLP1RMEN1KMT2ARECQLFAAH | |
| SCHEMBL14683589 | 0.93 | GLP1R (0.48) | GLP1RMEN1KMT2ARECQLFAAH | |
| SCHEMBL14683597 | 0.91 | GLP1R (0.43) | GLP1RMEN1KMT2AFAAH | |
| SCHEMBL14683599 | 0.89 | GLP1R (0.44) | GLP1RMEN1KMT2ARECQLFAAH | |
| SCHEMBL14685783 | 0.88 | GLP1R (0.54) | GLP1RMEN1KMT2ARECQLFAAH | |
| SCHEMBL14998226 | 0.87 | GLP1R (0.60) | GLP1R | |
| SCHEMBL12807268 | 0.87 | GLP1R (0.46) | GLP1RMEN1KMT2ARECQLFAAH | |
| SCHEMBL12743611 | 0.87 | GLP1R (0.46) | GLP1RMEN1KMT2ARECQLFAAH | |
| SCHEMBL14685781 | 0.81 | GLP1R (0.54) | GLP1RRECQLTSHREPHX2 | |
| SCHEMBL12807277 | 0.81 | GLP1R (0.54) | GLP1RMEN1KMT2ARECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815802-B2 | GLP-1 analogues and derivatives | NOVO NORDISK A/S (DK) | 2014-08-26 | — | — | US | disclosed |
| US-20130143798-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2013-06-06 | — | — | US | disclosed |
| US-20130053311-A1 | GLP-1 ANALOGUES AND DERIVATIVES | NOVO NORDISK A/S (DK) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143798-A1 | NOVEL GLUCAGON ANALOGUES | GLP1R, GCG, IAPP | GLP1R 1/4885MEN1 469/4885KMT2A 4093/4885 |
| US-20130053311-A1 | GLP-1 ANALOGUES AND DERIVATIVES | GLP1R, IAPP, SLC5A1 | GLP1R 1/4885MEN1 115/4885KMT2A 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.