Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14726159 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| SCHEMBL14726134 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| SCHEMBL14726106 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| SCHEMBL14726210 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| SCHEMBL14722506 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| SCHEMBL15018181 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL15879078 | 0.99 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL15879082 | 0.92 | KCNJ1 (0.50) | KCNJ1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL15879432 | 0.92 | KCNJ1 (0.50) | KCNJ1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL15018058 | 0.92 | KCNJ1 (0.50) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956142-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2013028474-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-02-28 | — | — | WO | disclosed |