⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL1774672 | 0.90 | — | — | |
| Butane SCHEMBL9060189 | 0.90 | — | — | |
| Butane SCHEMBL7063280 | 0.90 | — | — | |
| Butane SCHEMBL250788 | 0.78 | — | — | |
| Propanol SCHEMBL1922330 | 0.73 | — | — | |
| Pentane SCHEMBL28529129 | 0.73 | TSHR (0.58) | — | |
| Butane SCHEMBL483021 | 0.72 | — | — | |
| Butane SCHEMBL21562 | 0.72 | — | — | |
| Butane SCHEMBL10936920 | 0.72 | — | — | |
| Butane SCHEMBL3109038 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943647-B2 | Process for the preparation of tetrazole derivatives from organo aluminium azides | NOVARTIS AG (CH) | 2011-05-17 | — | — | US | claimed |
| EP-1646636-B1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | NOVARTIS AG (CH) | 2009-12-02 | — | — | EP | claimed |
| CN-110407898-B | Amphotericin B derivatives with improved therapeutic index | 伊利诺伊大学评议会 | 2023-12-01 | — | — | CN | disclosed |
| CN-110407898-A | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIV OF ILLIONIS | 2019-11-05 | — | — | CN | disclosed |
| CN-105848721-B | Amphotericin B derivatives with improved therapeutic index | 伊利诺伊大学评议会 | 2019-08-23 | — | — | CN | disclosed |
| CN-105848721-A | Amphotericin B derivatives with improved therapeutic index | 伊利诺伊大学评议会 | 2016-08-10 | — | — | CN | disclosed |
| US-8569528-B2 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | NOVARTIS AG (CH) | 2013-10-29 | — | — | US | disclosed |
| US-20120330026-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | NOVARTIS AG (CH) | 2012-12-27 | — | — | US | disclosed |
| US-20120238761-A1 | PROCESS FOR THE MANUFACTURE OF ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-09-20 | — | — | US | disclosed |
| EP-2493848-A1 | PROCESS FOR THE MANUFACTURE OF ORGANIC COMPOUNDS | Novartis AG (CH) | 2012-09-05 | — | — | EP | disclosed |
| US-20110184187-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | SEDELMEIER GOTTFRIED | 2011-07-28 | — | — | US | disclosed |
| WO-2007020654-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LOSARTAN | SUVEN LIFE SCIENCES (IN) | 2007-02-22 | — | — | WO | disclosed |
| US-20070043098-A1 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | NOVARTIS PHARMACEUTICALS CORPORATION | 2007-02-22 | — | — | US | disclosed |
| WO-2007009716-A1 | PREPARATION OF TERAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | disclosed |
| EP-1646636-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | Novartis AG (CH) | 2006-04-19 | — | — | EP | disclosed |
| US-6933002-B2 | Method for manufacturing organic EL device with protective layer | DENSO CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| WO-2005014602-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| US-6616972-B1 | Using as a precursor one or more of, and preferably a combination of, (RRN)xM(=NR)y and (RRN)xM(-R-N=C(R)(R))y where each R is H, alkyl or aryl and M is tantalum,niobium, tungsten or molydenum | AIR PRODUCTS AND CHEMICALS, INC. | 2003-09-09 | — | — | US | disclosed |
| US-20030129298-A1 | Method for manufacturing organic EL device with protective layer | TERA RYONOSUKE (JP) | 2003-07-10 | — | — | US | disclosed |
| US-20010031379-A1 | Organic EL device with protective layer | DENSO CORPORATION (JP) | 2001-10-18 | — | — | US | disclosed |