Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24686922 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDHTTDRD2CYP2C19 | |
| SCHEMBL14728245 | 0.92 | HPGD (0.36) | SMN1; SMN2HPGDHTTDRD2OPRK1 | |
| SCHEMBL14728243 | 0.92 | HPGD (0.36) | SMN1; SMN2HPGDHTTDRD2OPRK1 | |
| SCHEMBL13056339 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL13056342 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTDRD2CYP2C19 | |
| SCHEMBL17357524 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTDRD2CYP2C19 | |
| SCHEMBL10148003 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL13776353 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTDRD2CYP2C19 | |
| SCHEMBL13056345 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTDRD2CYP2C19 | |
| SCHEMBL18264887 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTDRD2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052130-A1 | Branched Discreet PEG Constructs | UNIVERSITY OF WASHINGTON (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130052130-A1 | Branched Discreet PEG Constructs | BTD, DNPEP, IDUA | SMN1; SMN2 3611/4885HPGD 734/4885HTT 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.