Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412287 | 0.85 | ESR2 (0.60) | TSHRARESR2KDM4EALDH1A1 | |
| SCHEMBL20405268 | 0.85 | ESR2 (0.63) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL222 | 0.85 | ESR2 (0.60) | TSHRARESR2KDM4EALDH1A1 | |
| SCHEMBL21189098 | 0.84 | TSHR (0.57) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL17033197 | 0.84 | TSHR (0.57) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL18406710 | 0.84 | TSHR (0.57) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL9313227 | 0.84 | TSHR (0.57) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL15536685 | 0.83 | TSHR (0.61) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL1132593 | 0.83 | TSHR (0.61) | TSHRLRRK2ARESR2LMNA | |
| SCHEMBL29293789 | 0.82 | TSHR (0.50) | TSHRLRRK2ARLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747238-A1 | PROCESS FOR PREPARING INTERMEDIATES OF SARTAN ACTIVE COMPOUNDS | Sanofi (FR) | 2026-05-27 | — | — | EP | claimed |
| CN-121586706-A | Process for the preparation of intermediates for sartan active compounds | 赛诺菲 | 2026-02-27 | — | — | CN | claimed |
| WO-2025021696-A1 | PROCESS FOR PREPARING INTERMEDIATES OF SARTAN ACTIVE COMPOUNDS | SANOFI (FR) | 2025-01-30 | — | — | WO | claimed |
| CN-118084811-B | Environment-friendly preparation method of sun-screening agent intermediate RET | 安庆科思化学有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118084811-A | Environment-friendly preparation method of sun-screening agent intermediate RET | 安庆科思化学有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-2194050-A1 | A new process for the preparation of irbesartan | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2010-06-09 | — | — | EP | claimed |
| US-6153810-A | Highly selective process for making o-arylbenzonitriles | OCCIDENTAL CHEMICAL CORPORATION (US) | 2000-11-28 | — | — | US | claimed |
| US-5874606-A | Process for making o-arylbenzonitriles | OCCIDENTAL CHEMICAL CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | claimed |
| EP-4747238-A1 | PROCESS FOR PREPARING INTERMEDIATES OF SARTAN ACTIVE COMPOUNDS | Sanofi (FR) | 2026-05-27 | — | — | EP | disclosed |
| CN-121586706-A | Process for the preparation of intermediates for sartan active compounds | 赛诺菲 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021696-A1 | PROCESS FOR PREPARING INTERMEDIATES OF SARTAN ACTIVE COMPOUNDS | SANOFI (FR) | 2025-01-30 | — | — | WO | disclosed |
| CN-118510512-A | Novel process for the preparation of 4'- (bromomethyl) [1,1' -biphenyl ] -2-carbonitrile | 阿尔第实业有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118084811-B | Environment-friendly preparation method of sun-screening agent intermediate RET | 安庆科思化学有限公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-0628046-A1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017023-A1 | PYRAZOLOPYRIMIDIN DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1993-09-02 | — | — | WO | disclosed |
| WO-1993017024-A1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1993-09-02 | — | — | WO | disclosed |
| CN-1055925-A | Pyridine derivate and preparation method thereof | ICI PLC (GB) | 1991-11-06 | — | — | CN | disclosed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |