Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 15/20 | 0.48 |
| ▸ | UBA3 | Q8TBC4 | 15/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14719969 | 0.81 | NAE1 (0.47) | NAE1UBA3ELOVL1 | |
| SCHEMBL23487450 | 0.74 | NAE1 (0.40) | NAE1UBA3 | |
| SCHEMBL23455999 | 0.74 | NAE1 (0.40) | NAE1UBA3 | |
| SCHEMBL23456099 | 0.70 | NAE1 (0.47) | NAE1UBA3 | |
| SCHEMBL27250596 | 0.69 | NAE1 (0.46) | NAE1UBA3ELOVL1 | |
| SCHEMBL15024140 | 0.67 | NAE1 (0.36) | NAE1UBA3ELOVL1 | |
| SCHEMBL18526987 | 0.65 | NAE1 (0.63) | NAE1UBA3ELOVL1 | |
| SCHEMBL14729632 | 0.64 | NAE1 (0.31) | NAE1UBA3 | |
| SCHEMBL23487922 | 0.63 | NAE1 (0.57) | NAE1UBA3 | |
| SCHEMBL23456068 | 0.63 | NAE1 (0.57) | NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028832-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-02-28 | — | — | WO | disclosed |