Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518879 | 0.86 | PDE10A (0.81) | PDE10A | |
| SCHEMBL520061 | 0.86 | PDE10A (0.76) | PDE10A | |
| SCHEMBL519124 | 0.86 | PDE10A (0.87) | PDE10A | |
| SCHEMBL15004887 | 0.86 | PDE10A (0.78) | PDE10A | |
| SCHEMBL15004950 | 0.85 | PDE10A (0.88) | PDE10A | |
| SCHEMBL15004699 | 0.85 | PDE10A (0.79) | PDE10A | |
| SCHEMBL520076 | 0.85 | PDE10A (0.87) | PDE10A | |
| SCHEMBL518500 | 0.84 | PDE10A (0.82) | PDE10A | |
| SCHEMBL30123152 | 0.84 | PDE10A (0.82) | PDE10A | |
| SCHEMBL519304 | 0.84 | PDE10A (0.82) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027845-A1 | RADIOLABELED COMPOUNDS AND THEIR USE AS RADIOTRACERS FOR QUANTITATIVE IMAGING OF PHOSPHODIESTERASE (PDE10A) IN MAMMALS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |