Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604811 | 0.91 | SYK (0.88) | SYKJAK2 | |
| SCHEMBL26389942 | 0.91 | SYK (0.88) | SYKJAK2 | |
| SCHEMBL18930353 | 0.90 | SYK (0.78) | SYKJAK2 | |
| SCHEMBL29635112 | 0.90 | SYK (0.76) | SYKJAK2 | |
| SCHEMBL14717004 | 0.90 | SYK (0.76) | SYKJAK2 | |
| SCHEMBL14716847 | 0.87 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL20376711 | 0.87 | SYK (0.74) | SYKJAK2 | |
| SCHEMBL30604892 | 0.87 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL14717145 | 0.86 | SYK (0.84) | SYKJAK2 | |
| SCHEMBL20376660 | 0.86 | JAK2 (0.77) | SYKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017095898-A1 | USES OF PYRIMIDO-PYRIMIDAZINONES TO TREAT CANCER | ASANA BIOSCIENCES, LLC (US) | 2017-06-08 | — | — | WO | disclosed |
| WO-2013028818-A1 | PYRIMIDO- PYRIDAZINONE COMPOUNDS AND USE THEREOF | ENDO PHARMACEUTICALS INC. (US) | 2013-02-28 | — | — | WO | disclosed |