Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 17/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14726486 | 0.91 | PIK3CG (0.47) | PIK3CGADORA1PIK3CDPIK3CBPIK3R1 | |
| SCHEMBL14730042 | 0.90 | PIK3CG (0.44) | PIK3CGPIK3CDPIK3CBPIK3R1PIK3CA | |
| SCHEMBL16119406 | 0.90 | PIK3CG (0.44) | PIK3CGADORA2AADORA1PIK3CDPIK3CB | |
| SCHEMBL18852732 | 0.88 | PIK3CG (0.43) | PIK3CGPIK3CDPIK3CBPIK3R1PIK3CA | |
| SCHEMBL14726841 | 0.88 | PIK3CG (0.46) | PIK3CGPIK3CDPIK3CBPIK3R1PIK3CA | |
| SCHEMBL14726488 | 0.87 | PIK3CD (0.52) | PIK3CGPIK3CDPIK3CBPIK3R1PIK3CA | |
| SCHEMBL14726754 | 0.85 | PIK3CD (0.53) | PIK3CGADORA2AADORA1PIK3CDPIK3CB | |
| SCHEMBL14726848 | 0.85 | PIK3CG (0.44) | PIK3CGPIK3CDPIK3CBPIK3R1PIK3CA | |
| SCHEMBL14729766 | 0.83 | PIK3CD (0.55) | PIK3CGADORA2AADORA1PIK3CDPIK3CB | |
| SCHEMBL14726492 | 0.82 | PIK3CG (0.46) | PIK3CGPIK3CDPIK3CBPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053362-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLKINE, LLC (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053362-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AKT3, PIK3CA, AKT1 | PIK3CG 14/4885ADORA2A 1341/4885ADORA1 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.