Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731491 | 0.85 | KDM4E (0.54) | KDM4EPKMPIK3CDKMT2ANPC1 | |
| SCHEMBL15014509 | 0.81 | KDM4E (0.59) | KDM4EPKMPIK3CDKMT2ANPC1 | |
| SCHEMBL12108494 | 0.79 | KDM4E (0.66) | KDM4EPKMPIK3CDKMT2ANPC1 | |
| SCHEMBL13779928 | 0.78 | KDM4E (0.68) | KDM4EPKMPIK3CDKMT2ANPC1 | |
| SCHEMBL27228782 | 0.77 | KDM4E (0.62) | KDM4EPKMPIK3CDKMT2AALDH1A1 | |
| SCHEMBL19710930 | 0.74 | PIK3CD (0.70) | KDM4EPKMPIK3CDKMT2ANPC1 | |
| SCHEMBL12385781 | 0.74 | KDM4E (0.56) | KDM4EPKMPIK3CDKMT2ANPC1 | |
| SCHEMBL12384440 | 0.74 | KDM4E (0.56) | KDM4EPKMPIK3CDKMT2AALDH1A1 | |
| SCHEMBL12424499 | 0.74 | KDM4E (0.56) | KDM4EPKMPIK3CDKMT2AALDH1A1 | |
| SCHEMBL24785483 | 0.73 | PIK3CD (0.48) | KDM4EPKMPIK3CDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026163-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |