Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956357 | 0.85 | AHR (0.59) | AHRCMA1HTR3AHTR3EHTR3B | |
| SCHEMBL14698684 | 0.81 | AHR (0.59) | DRD4AHRCMA1HTR3AHTR3E | |
| SCHEMBL29485904 | 0.80 | MAPT (0.62) | AHRCMA1HTR3AHTR3EHTR3B | |
| SCHEMBL6964275 | 0.80 | MAPT (0.62) | AHRCMA1HTR3AHTR3EHTR3B | |
| SCHEMBL14698807 | 0.77 | MAPT (0.53) | DRD4AHRHTR3ASCN9AHTR5A | |
| SCHEMBL2395389 | 0.73 | AHR (0.70) | AHRCMA1HTR3AHTR3EHTR3B | |
| SCHEMBL10507013 | 0.73 | AHR (0.50) | AHRCMA1HTR3AHTR3EHTR3B | |
| SCHEMBL426336 | 0.73 | NPC1 (0.55) | DRD4DRD2AHRMAPTMAOB | |
| SCHEMBL29754265 | 0.73 | AHR (0.70) | AHRCMA1HTR3AHTR3EHTR3B | |
| SCHEMBL16817933 | 0.71 | AHR (0.49) | DRD4AHRCMA1HTR3ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027932-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PREMATURE EJACULATION COMPRISING 8-HYDROXYCLOMIPRAMINE OR ITS SALT | KUHNIL PHARM. CO., LTD. (KR) | 2013-02-28 | — | — | WO | disclosed |