Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062266 | 1.00 | TYK2 (0.44) | TYK2PDE4DTTK | |
| SCHEMBL3775471 | 0.92 | TYK2 (0.46) | TYK2PDE4DTTK | |
| SCHEMBL3775469 | 0.92 | TYK2 (0.46) | TYK2PDE4DTTK | |
| SCHEMBL3769548 | 0.91 | TYK2 (0.45) | TYK2PDE4DTTK | |
| SCHEMBL3769543 | 0.91 | TYK2 (0.45) | TYK2PDE4DTTK | |
| SCHEMBL3780513 | 0.90 | TYK2 (0.46) | TYK2PDE4DTTK | |
| SCHEMBL3780517 | 0.90 | TYK2 (0.46) | TYK2PDE4DTTK | |
| SCHEMBL3781549 | 0.90 | TYK2 (0.49) | TYK2PDE4DTTK | |
| SCHEMBL3783025 | 0.90 | TYK2 (0.49) | TYK2PDE4DTTK | |
| SCHEMBL3821447 | 0.89 | TYK2 (0.44) | TYK2PDE4DTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389527-B2 | Substituted imidazopyridazines useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-03-05 | — | — | US | claimed |