Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882881 | 0.89 | CYP4F2 (0.32) | GRM5CYP4F2CYP4A11 | |
| SCHEMBL14733059 | 0.89 | CCR1 (0.42) | CCR1CCR8HSP90AA1CYP4F2CYP4A11 | |
| SCHEMBL14732923 | 0.89 | CCR1 (0.42) | CCR1CCR8HSP90AA1CYP4F2CYP4A11 | |
| SCHEMBL14733133 | 0.88 | FFAR1 (0.36) | CCR1CCR8HSP90AA1 | |
| SCHEMBL5020221 | 0.85 | GRM5 (0.34) | GRM5CCR1CCR8HSP90AA1CYP4F2 | |
| SCHEMBL15465604 | 0.85 | GRM5 (0.34) | GRM5CCR1CCR8HSP90AA1CYP4F2 | |
| SCHEMBL15465601 | 0.85 | GRM5 (0.34) | GRM5CCR1CCR8HSP90AA1CYP4F2 | |
| SCHEMBL14732908 | 0.82 | CCR1 (0.42) | GRM5CCR1CCR8HDAC1HDAC8 | |
| SCHEMBL5020222 | 0.81 | NPC1 (0.39) | GRM5CCR1CCR8HSP90AA1 | |
| SCHEMBL14732987 | 0.81 | GRM5 (0.36) | GRM5CCR1CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |