Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567287 | 0.95 | PDK2 (0.31) | PDK2 | |
| SCHEMBL19607479 | 0.88 | PDK2 (0.41) | PDK2 | |
| SCHEMBL19792212 | 0.77 | GSK3B (0.42) | PDK2 | |
| SCHEMBL21841881 | 0.75 | — | — | |
| SCHEMBL12954345 | 0.71 | — | — | |
| SCHEMBL206283 | 0.70 | PDK2 (0.48) | PDK2 | |
| SCHEMBL13107406 | 0.70 | PDK2 (0.48) | PDK2 | |
| SCHEMBL17474763 | 0.70 | PDK2 (0.48) | PDK2 | |
| SCHEMBL22926653 | 0.70 | KDM4E (0.41) | PDK2 | |
| SCHEMBL21416434 | 0.70 | KDM4E (0.41) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017072596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LEDIPASVIR | OPTIMUS DRUGS (P) LTD (IN) | 2017-05-04 | — | — | WO | disclosed |
| WO-2013028953-A1 | COMBINATION TREATMENTS FOR HEPATITIS C | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |