Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733229 | 0.90 | CYP3A4 (0.85) | CYP3A4GNRHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14733233 | 0.87 | CYP3A4 (0.77) | CYP3A4GNRHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14733232 | 0.87 | CYP3A4 (0.77) | CYP3A4GNRHRCYP1A2CYP2C9CYP2C19 | |
| Am-461 SCHEMBL29567409 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP1A2CYP2C9CYP2C19EPHX2 | |
| Am-461 SCHEMBL349848 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP1A2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL2361747 | 0.87 | CYP3A4 (0.85) | CYP3A4GNRHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14733234 | 0.86 | CYP3A4 (0.75) | CYP3A4GNRHRCYP1A2CYP2C9CYP2C19 | |
| Am-461 SCHEMBL14715970 | 0.86 | CYP3A4 (0.84) | CYP3A4GNRHRCYP1A2CYP2C9CYP2C19 | |
| Am-461 SCHEMBL14715969 | 0.86 | CYP3A4 (0.98) | CYP3A4CYP1A2CYP2C9CYP2C19EPHX2 | |
| Am-461 SCHEMBL14715972 | 0.86 | CYP3A4 (0.98) | CYP3A4CYP1A2CYP2C9CYP2C19EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053444-A1 | DP2 ANTAGONIST AND USES THEREOF | PANMIRA PHARMACEUTICALS, LLC (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053444-A1 | DP2 ANTAGONIST AND USES THEREOF | PTGER2, PTGDR2, PTGES2 | CYP3A4 2497/4885GNRHR 2609/4885CYP1A2 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.