Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033475 | 0.92 | CYP3A4 (0.76) | CYP3A4EPHX2ALDH1A1PTGDR2KDM4E | |
| SCHEMBL14733229 | 0.86 | CYP3A4 (0.85) | CYP3A4EPHX2MTNR1AMTNR1BPTGDR2 | |
| SCHEMBL14733232 | 0.83 | CYP3A4 (0.77) | CYP3A4EPHX2MTNR1AMTNR1BPTGDR2 | |
| SCHEMBL14733241 | 0.83 | CYP3A4 (0.68) | CYP3A4EPHX2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14733233 | 0.81 | CYP3A4 (0.77) | CYP3A4EPHX2MTNR1AMTNR1BPTGDR2 | |
| SCHEMBL14733234 | 0.80 | CYP3A4 (0.75) | CYP3A4EPHX2PTGDR2SMN1; SMN2POLB | |
| SCHEMBL349807 | 0.79 | CYP3A4 (0.79) | CYP3A4EPHX2PTGDR2SMN1; SMN2POLB | |
| SCHEMBL2361747 | 0.78 | CYP3A4 (0.85) | CYP3A4EPHX2MTNR1AMTNR1BALDH1A1 | |
| Am-461 SCHEMBL349848 | 0.78 | CYP3A4 (1.00) | CYP3A4EPHX2ALDH1A1PTGDR2SMN1; SMN2 | |
| Am-461 SCHEMBL29567409 | 0.78 | CYP3A4 (1.00) | CYP3A4EPHX2ALDH1A1PTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688624-B2 | DP2 antagonist and uses thereof | BRICKELL BIOTECH, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20130053444-A1 | DP2 ANTAGONIST AND USES THEREOF | PANMIRA PHARMACEUTICALS, LLC (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053444-A1 | DP2 ANTAGONIST AND USES THEREOF | PTGER2, PTGDR2, PTGES2 | CYP3A4 2497/4885EPHX2 218/4885MTNR1A 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.