Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733584 | 1.00 | FFAR1 (0.40) | FFAR1PPARGADRB3ADRB1TBXA2R | |
| SCHEMBL14213635 | 0.95 | FFAR1 (0.39) | FFAR1PPARGADRB3ADRB1ADRB2 | |
| SCHEMBL14213632 | 0.95 | FFAR1 (0.39) | FFAR1PPARGADRB3ADRB1ADRB2 | |
| SCHEMBL14213669 | 0.90 | FFAR1 (0.41) | FFAR1PPARGADRB3ADRB1ADRB2 | |
| SCHEMBL14733581 | 0.89 | PPARG (0.49) | FFAR1PPARGPTGFRCYP2C9 | |
| SCHEMBL14733582 | 0.89 | PPARG (0.49) | FFAR1PPARGPTGFRCYP2C9 | |
| SCHEMBL14733583 | 0.89 | PPARG (0.49) | FFAR1PPARGPTGFRCYP2C9 | |
| SCHEMBL14213630 | 0.87 | PPARG (0.41) | FFAR1PPARGADRB3ADRB1ADRB2 | |
| SCHEMBL14213708 | 0.87 | PPARG (0.41) | FFAR1PPARGADRB3ADRB1ADRB2 | |
| SCHEMBL14213770 | 0.84 | FFAR1 (0.40) | FFAR1PPARGPTGFRCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053350-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | METABOLIC SOLUTIONS DEVELOPMENT COMPANY, LLC (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053350-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PPARD, PPARG, PPARA | FFAR1 75/4885PPARG 2/4885ADRB3 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.