⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438732 | 1.00 | — | — | |
| SCHEMBL771996 | 0.93 | — | — | |
| SCHEMBL4420100 | 0.81 | — | — | |
| SCHEMBL12371218 | 0.79 | CYP1A2 (0.50) | — | |
| SCHEMBL9996729 | 0.78 | CYP1A2 (0.50) | — | |
| SCHEMBL294017 | 0.77 | — | — | |
| SCHEMBL8325168 | 0.77 | — | — | |
| SCHEMBL10206077 | 0.77 | — | — | |
| SCHEMBL23844550 | 0.75 | CYP1A2 (0.57) | — | |
| SCHEMBL1371466 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227263-B1 | CXCR7 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-04-10 | — | — | EP | claimed |
| US-10202368-B2 | CXCR7 receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2019-02-12 | — | — | US | claimed |
| CN-105555761-B | Biphenyl derivatives and process for preparing the same | 东亚ST 株式会社 | 2018-12-11 | — | — | CN | claimed |
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |
| US-9920010-B2 | CXCR7 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-03-20 | — | — | US | claimed |
| US-9828339-B2 | Biphenyl derivatives and methods for preparing same | DONG-A ST CO., LTD (KR) | 2017-11-28 | — | — | US | claimed |
| US-20170327493-A1 | CXCR7 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-11-16 | — | — | US | claimed |
| EP-3227263-A1 | CXCR7 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd (CH) | 2017-10-11 | — | — | EP | claimed |
| EP-3004082-B1 | CXCR7 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-08-02 | — | — | EP | claimed |
| CN-106687114-A | Pyrimidine compounds and methods using the same | 尤马治疗公司 | 2017-05-17 | — | — | CN | claimed |
| US-6239142-B1 | HERPES VIRUS INFECTION | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | claimed |
| WO-2001025203-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-12 | — | — | WO | claimed |
| WO-2001004102-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 2001-01-18 | — | — | WO | claimed |
| EP-0736039-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2000-10-25 | — | — | EP | claimed |
| WO-2000053610-A2 | 4-OXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-14 | — | — | WO | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| US-5668165-A | TREATMENT OF HIV INFECTIONS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | claimed |
| EP-0252299-A2 | Use of 12-amino-pyridazino[4',5':3,4]pyrrolo[2,1-a]isoquinolines in the preparation of cardioprotective and neuroprotective agents | BOEHRINGER INGELHEIM KG (DE) | 1988-01-13 | — | — | EP | claimed |
| EP-0029286-A1 | Pyrrolo(3,4-c)quinoline derivatives, processes therefor, and pharmaceutical compositions | ICI AMERICAS INC. (US) | 1981-05-27 | — | — | EP | claimed |
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | claimed |