Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583912 | 0.90 | HDAC4 (0.41) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL14735825 | 0.90 | HDAC4 (0.42) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL2588936 | 0.87 | MEN1 (0.41) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL14737275 | 0.86 | PDE4D (0.39) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL14736988 | 0.85 | PDE4D (0.39) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL14736700 | 0.85 | PDE4D (0.38) | ALDH1A1HDAC4HDAC2HDAC8POLB | |
| SCHEMBL17599631 | 0.85 | HDAC4 (0.39) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL2588301 | 0.85 | PDE4D (0.45) | HPGDALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL2585728 | 0.84 | PDE4D (0.40) | HDAC4HDAC2HDAC8SMN1; SMN2KDM4E | |
| SCHEMBL14737352 | 0.84 | PDE4D (0.38) | HPGDALDH1A1HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563770-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2013-03-06 | — | — | EP | disclosed |